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Another Culprit In Breast Cancer - Senior Health - Healthy Aging - Health For Seniors
Another Culprit In Breast Cancer - Senior Health - Healthy Aging - Health For Seniors
Another Culprit In Breast Cancer

BRCA1 has been getting a lot of press because mutations in the gene are responsible for about 3 percent of all cases of breast cancer.

But there might be an even worse villain. Researchers from the Howard Hughes Medical Institute at Baylor College of Medicine have identified a protein that triggers the mouse version of the BRCA1 protein to initiate the repair of damaged DNA.

They say that mutations in the human gene that produces this trigger protein are likely to be responsible for more instances of breast cancer than BRCA1 mutations.

The discovery of the trigger protein, made by a gene called ATM, suggests that malfunctions in BRCA1 and ATM combined may account for nearly 10 percent of all breast cancers, said lead study author and HHMI investigator Stephen Elledge.

The results were reported in the journal Science.

Another Culprit In Breast Cancer
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